Pore-clogging ingredients / Isopropyl Palmitate

Is Isopropyl Palmitate comedogenic?

Yes. This ingredient clogs pores for many people.

Comedogenic rating
4/5
Highly comedogenic
Evidence confidence
high
Published lists agree on this rating.
Also appears as
ipp

What is Isopropyl Palmitate?

A synthetic ester of isopropyl alcohol and palmitic acid, close cousin to isopropyl myristate. It gives creams and lotions a silky, non-oily slip and acts as a binder in pressed powders, so it appears across moisturizers, foundations, and conditioners.

What to do if you're acne-prone

Skip it in leave-on products like moisturizers, sunscreens, and foundations if you're acne-prone. In rinse-off products the risk is lower but not zero.

Where this rating comes from

Our ratings consolidate two lineages: the original rabbit-ear comedogenicity assays published by James Fulton and colleagues (Fulton, Pay & Fulton, Journal of the American Academy of Dermatology, 1984; Fulton, Journal of the Society of Cosmetic Chemists, 1989), and the pore-clogger lists maintained by acne-specialist estheticians in the Face Reality lineage that refine those assays with decades of client observation. Both source lineages agree on this ingredient's rating.

Last reviewed 2026-08-15 by the PorePass editorial team.

Checking labels for Isopropyl Palmitate by hand?

Paste any product's full ingredient list and we'll flag this and 99 other pore-cloggers, including synonyms and misspellings, in one click.

Check a product free

Related pore-clogging ingredients

Comedogenicity ratings come from published ingredient studies and esthetician-compiled lists. They are imperfect and formulation-dependent, and this page isn't medical advice. Reactions vary by skin, concentration, and the rest of the formula.