Pore-clogging ingredients / CI 45380

Is CI 45380 comedogenic?

It can. This ingredient carries moderate pore-clogging risk.

Comedogenic rating
3/5
Moderately comedogenic
Evidence confidence
moderate
Most published lists include this ingredient, with ratings that vary by about one point.
Also appears as
d&c red 21, d&c red 22, red 21, red 22

What to do if you're acne-prone

Position matters: high on the ingredient list means more of it in the formula. If you're very breakout-prone, choose an alternative; otherwise watch how your skin responds.

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Other ingredients rated 3/5

Comedogenicity ratings come from published ingredient studies and esthetician-compiled lists. They are imperfect and formulation-dependent, and this page isn't medical advice. Reactions vary by skin, concentration, and the rest of the formula.